Co-factors of DAO (diamine oxidase)

Information on the test for DAO cofactors

This laboratory test detects the cofactors of diamine oxidase (DAO) , particularly vitamin B6, zinc, and copper . These micronutrients are relevant for the function of the DAO enzyme and indirectly support the breakdown of histamine in the body.

The test is frequently used in connection with histaminosis or when impaired histamine processing is suspected.

What are cofactors?

Cofactors are substances that support enzymatic processes without being the enzyme itself. In the case of diamine oxidase (DAO), vitamin B6, zinc, and copper contribute to the efficient breakdown of histamine . A deficiency of one or more of these cofactors can impair DAO activity.

When is the test useful?

Determining DAO cofactors can be considered:

• in case of suspected histamine intolerance
• if there are indications of limited DAO activity
• for supplementary clarification in cases of unclear histamine-associated symptoms

The test serves to classify possible influencing factors and does not replace a medical assessment.

Contextualization

Measuring cofactors is a useful complement to determining DAO activity. Together, these parameters can help to consider possible causes of impaired histamine processing in a more differentiated way.

Further information on the topic of histamine intolerance may be helpful for better understanding.

Implementation and evaluation

This test requires a blood sample . The cofactor analysis is performed in the laboratory .

If you live nearby, please feel free to contact us. We can inform you about locations where blood can be drawn in your area . Alternatively, you can contact a healthcare professional you trust .

Result and classification

The test results can provide information about the supply of relevant DAO cofactors .
If the result is abnormal or unclear, it is recommended that you contact a medical professional for further evaluation . Further information on histamine intolerance can be found here .

Scope of delivery and execution